Michael Oellerich, MD, HonMD, FAACC, FAMM, FFPath (RCPI), FRCPath, is a chemical pathologist and currently a Distinguished Research Professor at the Department of Clinical Pharmacology, Medical Faculty (UMG) of the George-August University, Göttingen, Germany. From 2012 to 2017 he had an appointment as Lower Saxony Professor of Clinical Chemistry. He was Chairman of the Department of Clinical Chemistry/Central Laboratory at UMG (1991-2012), and Dean of the Faculty of Medicine. He served as President of national and international professional organizations (IATDMCT, DGLM, DGKL, WASPaLM). He was Editor-in-Chief of Therapeutic Drug Monitoring (2003-2018) and currently is Associate Editor of this journal. His current research interests are in the field of therapeutic drug monitoring (e.g. cfDNA in cancer and donor-derived cell-free DNA in transplantation). He has authored more than 500 publications and has received various awards (e.g. Ludolf-Krehl Award, IATDMCT Charles Pippenger Award, WASPaLM Medal of Honor, WASPaLM Gold-Headed Cane, Sign of Honor, Professor Jordan Todoroff (BSCL). F. McCreary Prize for Interprofessional Teamwork, Genome Canada Transplant Consortium, University of British Columbia, UBC Health, Vancouver (Canada) 2022, Claus Roxin Award for Outstanding Contributions to International Liberal Academic Exchange, Munich 2023).
Office
| Assistant: | Kirsten Bornemann | |
| Tel.: | +49 551 39 - 68562 | |
| Fax: | +49 551 39 - 68551 | |
| Email: | michael.oellerich@med.uni-goettingen.de | |
| Medical Faculty (UMG) of the George-August University Göttingen | ||
| Department of Clinical Pharmacology | ||
| Kreuzbergring 36 | ||
| D-37075 Göttingen | ||
| Germany |
Research activities
Specific areas of research currently encompass therapeutic drug monitoring, pharmacokinetics, pharmacogenetics and pharmacodynamics with particular focus on molecular biomarkers to achieve personalized immunosuppression in transplantation (e.g. donor-derived cell-free DNA) as well as genotype-directed cancer care using ctDNA; research recently published in the American Journal of Transplantation (Oellerich M et al, Absolute quantification of donor-derived cell-free DNA as a marker of rejection and graft injury in kidney transplantation: Results from a prospective observational study) was among the top 10% most downloaded papers in 2019.
Research projects
| 1993 - 1995 | SFB 330 |
| Organprotektion | |
| Teilprojekt D8 | |
| Organprotektion: Lipidperoxidation und Cytochrom P-450 Aktivität in der Leber im Ischämieverlauf und nach Reperfusion | |
| Oellerich / Wieland /Schuff-Werner | |
| 1998 - 2000 | SFB 402 |
| Molekulare und Zelluläre Hepaterogastroenterologie | |
| Teilprojekt D 1 | |
| Mechanismen des Konservierungs- / Reperfusionsschadens und dessen Bedeutung für den Funktionserhalt von Leber und Dünndarm des Schweins | |
| Schütz / Oellerich / Wieland / Braun / Ringe | |
| 1999 - 2001 | SFB 500 |
| Maligne Transformation und Tumorprogression | |
| Teilprojekt B1 | |
| Bedeutung der induzierbaren NO-Synthese (iNOS) für die TNF-a-induzierte Apoptose von epithelialen Tumorzellen | |
| Binder / Oellerich | |
| 2001 - 2003 | QLRI-CT-2002-02758-EUPEAH |
| Glucocorticoid Hormone Programming in Early Life and its Impact on Adult Health (EUPEAH) | |
| Oellerich / Armstrong | |
| 2007 - 2012 | BMBF Projekt Indien IND 06/040 |
| Studies on Aspergillus fumigatus proteome for identification of novel unknown immunogens | |
| Oellerich / Asif / Reichard | |
| Sharma / Bhadoria / Katyal / Singh / Kumar | |
| 2012 - 2015 | BMBF Projekt 01ES1102 |
| Biomarker assisted personalized immunosuppression following liver transplantation | |
| Brockmöller / Oellerich / Nashan / Pratschke / Friede / Kollmar / Schemmer | |
| 2015 - 2018 | KMU-Innovativ: Biotechnologie – BioChance, Nr. PtJ 31P9146 (BIO-624-004) |
| Validierung eines GcfDNA-basierten diagnostischen Tests zur frühzeitigen Erkennung von Organschädigungen nach Nierentransplantation | |
| Schütz / Oellerich / Friede / Wieland | |
| 2018 - 2022 | Genome Canada large-scale applied research project (LSARP): Precision Medicine CanPREVENT AMR: Applying Precision Medicine Technologies in Canada to Prevent Antibody Mediated Rejection and Premature Kidney Transplant Loss (273AMR) |
| Keown / Sapir-Pichhadze / Caulfield / Bryan Oellerich (co-investigator) | |
| 2019 - | Cell-free donor-DNA monitored personalized immunosuppression after liver transplantation – a prospective oberservation single center study. |
| Medizinische Hochschule Hannover, Abteilung Gastroenterologie, Hepatologie und Endokrinologie | |
| Tauber / Oellerich / Schütz / Beck | |
| 2021 - 2023 | Donor-derived cell-free DNA for early diagnosis of antibody-mediated rejection (cfDNA-DSA) (NCT 04897438). (Pilotstudie zur prospektiven Evaluation zellfreier Transplant_DNA in der Diagnostik von Patient*innen mit donorspezifischen HLA_Antikörpern nach Nierentransplantation). |
| Charite – Universitätsmedizin Berlin, Abteilung Nephrologie und Intensivmedizin | |
| Budde / Oellerich / Osmanodja / Beck / Bornemann-Kolatzki / Schütz |
Research partners
| Dr. rer.nat. Julia Beck | Chronix Biomedical, Göttingen, Germany |
| Dr. Ortraud Beringer | Department of Pediatrics and Adolescent |
| Dr. med.vet. Kirsten Bornemannolatzki | Chronix Biomedical, Göttingen, Germany |
| Prof. Dr. Klemens Budde | Division of Nephrology and Internal Intensive Care Medicine, Hospital Charité Universitätsmedizin Berlin, Germany |
| PD Dr.med. Dr. rer.nat. Ingvild Birschmann | Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center NRW, Bad Oeynhausen, Germany |
| Prof. Dr.med. Jürgen Brockmöller | Dept. of Clinical Pharmacology, University Medical Center Göttingen, Germany |
| Prof. Dr.med. Martin Canis | Dept. of Otolaryngology, Hospital of the Ludwig-Maximilians-University (LMU) Munich, Germany |
| Prof. Dr.med. Jan Gummert | Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, Bad Oeynhausen, Germany |
| Prof. Dr. Paul A. Keown, MD | Dept. of Immunology, University of British Columbia, Vancouver, Canada |
| Dr.med. Bilgin Osmanodja | Division of Nephrology and Internal Intensive Care Medicine, Hospital Charité Universitätsmedizin Berlin, Germany |
| Prof. Dr.med. L. Christian Rump | epartment of Internal Medicine / Nephrology, University Medical Center Düsseldorf, Germany |
| Prof. Dr.med. Ekkehard Schütz | Chronix Biomedical, Göttingen, Germany |
| Karen Sherwood, PhD | Dept. of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada |
| Prof. Dr.med. Vedat Schwenger | Clinic for Kidney, Hypertension and Autoimmune Diseases, Katharinenhospital, Klinikum Stuttgart, Germany |
| Dr. med. Dr. b-g Maria Shipkova | Synlab Holding Germany GmbH, Competence Center for Therapeutic Drug Monitoring, Medical Care Center, Leinfelden-Echterdingen, Germany |
| PD Dr.med. Johannes Stegbauer | Department of Internal Medicine / Nephrology, University Medical Center Düsseldorf, Germany |
| PD Dr. Richard Taubert, MD | Dept. of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hanover, Germany |
| Prof. Dr. med. Burkhard Tönshoff | University Children's Hospital Heidelberg, Germany |
| Prof. Philip D. Walson, MD | Dept. of Clinical Pharmacology, University Medical Center Göttingen, Germany |
| Prof. Dr.med. Eberhard Wieland | Synlab Holding Germany GmbH, Competence Center for Therapeutic Drug Monitoring, Medical Care Center, Leinfelden-Echterdingen, Germany |
| Prof. George Yousef, MD, PhD | Department of Laboratory Medicine & Pathobiology - Anatomic Pathology, Toronto General Hospital: University Health Network (UHN), Canada |
Teaching
Clinical chemistry lectures, seminars
Events
